- Leica DMi8 inverted research microscope designed for advanced cell imaging and fluorescence microscopy workflows.
- Modular platform with integrated brightfield and fluorescence optical paths for flexible imaging configurations.
- Motorized components provide automated control of stage movement, focus, condenser, and filter turret.
- Six-position motorized objective nosepiece allows rapid switching between multiple magnifications.
- Adaptive Focus Compensation maintains stable focus during long-term live-cell imaging.
- Compatible with external fluorescence light sources and multiple filter cubes for multi-channel imaging.
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Leica DMi8 Inverted LED Fluorescence Motorized Microscope w/ Adaptive Focus Control (New Filters)
- Stock: In Stock
- Brand: Leica
- Product Code: 66024
$44,995.00
For Sale Leica DMi8 Inverted LED Fluorescence Motorized Microscope w/ Adaptive Focus Control
- Fully Functional
- Serviced & in Stock
- Customized to your requirements
- Includes new fluorescence filters
- Technical sales consultation available
- Continental USA 120 DAYS WARRANTY & 60 DAYS INTERNATIONAL
- Includes remote microscope training session and software overview
Service Highlights
- Optics quality is checked for field distortion and uniformity at the specimen plane
- Fluorescence Intensity is also measured at the specimen plane to confirm light source and filter performance
- Preventive Maintenance (PM) is Completed
Predecessor to Leica DMi8 S
This is what you will receive before customizing this microscope:
Standard Leica DMi8 Inverted Microscope Configuration:
Microscopy Techniques:
Brightfield and Fluorescence Microscopy
Microscope Base:
- Leica DMi8 Inverted Microscope w/ Adaptive Focus Compensation (AFC)
- CTR Control Box
Microscope Head:
- Binocular Head
- HC PLAN s 10x/25 Eyepiece (Qty. 2)
Fluorescence Light Path:
- Built-in
Fluorescence Illumination:
- EXFO X-Cite XLED w/ Light Guide
Fluorescence filter cube turret:
- 6-position Motorized Reflector Turret
- Additional Infinity Port Fluorescence Axis
Fluorescence filters:
- Three empty filter cubes
- Three Brand New filter sets of either DAPI, FITC, Texas Red or CY3
Brightfield Light Path:
- Built-in
Brightfield Illumination:
- 12V TL LED Lamp
Objective Turret:
- 6-position Motorized Nosepiece
Objectives:
- 5x/0.12 HCX FL PLAN
- 10x/0.30 HX PL FLUOTAR Ph1
- 40x/0.60 HCX PL FLUOTAR L Ph2
- *Other objectives are available - please inquire*
Condenser:
- 0.55 Motorized Condenser
Stage:
- Motorized Leica w/ Smartmove Joystick
Camera ports:
- 100% - Eye
- 50%/50% - Left Port/Eye
- 100% - Left Port
- 100% - Right Port
Camera:
- Leica DFC7000T CCD Camera
Computer & Software:
- Computer running Leica LAS X software and Micro-Manager software
LAS Software with licenses for:
- Mark and Find
- Time Lapse
- Multi-channel acquisition
- Z-control & Autofocus
- Mosaic Plus
- 3d Advanced Basic
- Mobile Devices
- Environmental Control
- Assay Editor
Accessories:
- Necessary power and communication cables
This configuration includes any 3 of these new filter sets.
- New filter set - DAPI (EX: 365/28nm, DM: 405nm, EM: 445/50nm) (Dye compatibility: DAPI/Hoechst/AlexaFluor 350)
- New filter set - EGFP/FITC/Cy2 (EX: 475/30nm, DM: 500nm, EM: 530/40nm) (Dye compatibility: EGFP/FITC/Cy2/AlexaFluor 488)
- New filter set - TRITC/Cy3/Dsred (EX: 545/20nm, DM: 562nm, EM: 605/60nm) (Dye compatibility: TRITC/Cy3/RFP/Rhodamine/AlexaFluor 546)
- New filter set - Texas Red (EX: 560/20nm, DM: 585nm, EM: 630/40nm) (Dye compatibility: Texas Red/mCherry/AlexaFluor 594)
- New filter set - Cy5 (May require an upgraded light source) (EX: 630/50nm, DM: 662nm, EM: 695/50nm) (Dye compatibility: Cy5/AlexaFluor 647/Draq5)
Automated/motorized capabilities of this microscope:
Installed automation/motorized components:
- Motorized XY Stage
- Motorized/automated Z-Axis Drive
- Motorized filter cube turret
- Motorized objective(nosepiece) turret
- Motorized condenser
- Motorized EPI Fluor Path Shutter
- Motorized Light Source Intensity
Benefits of motorized/Automated Z-Axis drive:
- Automatic parfocality adjustment
- The ability to recall previously saved focus levels
- Automated management of Z positioning/ Fine-coarse control
This microscope's imaging capabilities:
Imaging software highlights:
- Ability to take still images and live videos of your samples
- Display, annotate, edit, calibrate, measure, analyze, process, print, and save raster
- Variable linear measurements such as line segment, radius values, and others
- Open source Micromanager Multi-dimensional Image acquisition & automation software capabilities
- Multi-frame (Time lapse/Image acquisition over time)
- Multi-slice (Z coordinate/Z Stacking)
- *Multi-position (XY coordinate/Stitching/Mosaic) – only available when equipped with a motorized XY Stage
We can customize this microscope to fit your requirements:
Add Microscopy Techniques (In addition to installed Brightfield and Fluorescence)
- Phase Contrast, DIC, or Polarization Add-on Components may be added (subject to availability)
Increase Maximum Magnification and Image Quality:
- Microscope can be configured for magnification between 50x and 400x (with 10x Eyepieces)
- We can add standard higher magnification Leica microscope objectives
- We can add high-end Leica Apochromat objectives
Enhance fluorescence capabilities by adding/changing filters and upgrading light sources.
- Additional filter cubes
- Additional filter sets to match your fluorochromes.
- Xenon, Metal Halide, or LED Fluorescence microscope light sources
We will also ensure the fluorescence light source matches your selected filter sets.
Enhance imaging capabilities:
- We offer various advanced CCD, sCMOS, and EMCCD camera options for higher-quality images.
We can configure it to work with the sample medium you need:
- Slide, Petri dish, microplate, etc.
Commonly Requested Customer Upgrades
- High-End CCD, sCMOS Cameras
- LED or Metal Halide Fluorescence Light Sources
- Phase Contrast, Polarization, or the DIC configurations
- Higher Magnification Objectives
- Higher performance Fluor or APO objectives
- Motorized XY Stage (stage, controller, joystick)
We are excited to help build and configure the right microscope for you!
Leica DMi8 Inverted Microscope Overview
(Final microscope capabilities will depend on the modifications you request)
Suited for the following applications as configured:
- Live cell imaging and long-term cell culture observation.
- Fluorescence imaging of labeled cellular structures.
- Multichannel fluorescence experiments using interchangeable filter cubes.
- High-resolution brightfield imaging of cultured cells and tissues.
- Time-lapse microscopy with automated focus and stage control.
- Automated imaging workflows requiring motorized microscope components.
Other potential applications:
- Advanced fluorescence imaging with additional filter configurations.
- High-content screening and automated image acquisition.
- Co-localization studies using multi-channel fluorescence labeling.
- Quantitative imaging for biological and biomedical research.
- Long-term environmental and incubation-based cell imaging.
- Integration with advanced cameras or imaging modules for specialized workflows.
Video Overview:
REASONS WHY THESE CUSTOMERS CHOOSE TO ORDER FROM US
- They want to ensure the microscope is customized to fit their application
- They want to ensure that internal optics are properly cleaned
- They want to ensure that internal mechanical and motorized mechanisms are lubricated and aligned
- They want to ensure that image quality is verified at the sample point for field distortion and uniformity
- They want to ensure that the fluorescence intensity is verified at the sample point
- They want to ensure NEW fluorescence filters are installed just the same as buying a new microscope
- They want to ensure that if paired with a motorized XY stage, it is lubricated and does not skip steps
- They want an option to upgrade the camera to sCMOS and the light source to Lumencor or X-Cite LED
- They want training to learn how to operate the microscope
- They want a reliable warranty
- They want peace of mind knowing it will be safely and professionally packed for shipping
- We make sure to match the microscope capabilities to your requirements.
- We have experience servicing and repairing these microscopes.
- This microscope goes through an extensive set of service steps before shipping.
- We offer detailed photos and videos of the microscopes you buy.
- We are an approved pre-owned equipment vendor to many large US, Canadian, and EU Universities.
- We are an approved pre-owned equipment vendor to many Fortune 500 US and International Biopharma companies.
- Many upgrade and repair parts are in stock.
- Remote installation and microscope operation training are available.
- On-site installation may be available in the Boston Area (New England area)
- Expert US or International shipping is available (see the shipping tab on how we pack and feel at ease)
- Warranty
- An extended warranty may be available.
- You get after-sales technical support.
- Customer references are available.
- The microscope will be complete and working!
- Smooth process from the initial quote to order fulfillment.
*SM* Small Crate
300#
COMMON CUSTOMER QUESTIONS AND ANSWERS BELOW
What steps do you take to verify, service, and confirm the functionality of the Leica DMi8 Inverted Microscope?
We verify various microscope functions individually and together, performing necessary repairs or maintenance to bring the microscope to our quality standards.
- We confirmed the functionality of the LED lamp and light source.
- We evaluated the transmitted brightfield light path.
- We operated and confirmed performance of the Spectra fluorescence light source.
- We assessed the functionality of the AFC system.
- We inspected the fluorescence light path.
- We verified proper switching of the port splitter between the camera and eyepieces.
- We checked the operation of the motorized condenser.
- We validated the movement of the motorized Z-axis.
- We confirmed the operation of the motorized fluorescence filter turret.
- We checked the functionality of the motorized objective turret.
- We verified smooth movement of the motorized XY stage.
- We confirmed the camera connection to the laptop.
- We evaluated the live camera feed for image clarity.
- We inspected the objectives and confirmed clear image quality.
Can you help me identify the best microscope and configuration for me?
We are here to help.
- Contact us with your application; we will help you identify the best microscope configuration.
- We do not believe in a one-size-fits-all approach; you should get a microscope that will do what you need.
Can I view the Leica DMi8 Inverted Microscope in person at your facility or do a live Zoom demo before it is shipped to me?
We invite you to visit our facility for an on-site demo, or feel free to request a virtual Zoom demo of the microscope you are interested in.
What about the warranty? Installation, training, maintenance?
Warranty Terms:
- The microscope is fully warranted for parts and labor.
- The customer should retain all packing materials during the warranty period.
Installation & Training:
Option 1 – In Person
If your lab is located within two hours of Boston, we may be able to offer in-person installation and training in person.
Option 2 – Remote/Virtual
Our remote training is conducted via Zoom, allowing us to significantly reduce its cost and offer it to customers outside our travel area.
Both training options include:
- Review of the microscope and its capabilities.
- Microscope and software operation.
- Review of the recommended maintenance procedures.
We generally recommend these training services to anyone who is new to this microscope model.
What should I watch out for when buying a Leica DMi8 Inverted Microscope used/pre-owned from another lab?
- Make sure the microscope is properly packed for shipping and will arrive safely. If the microscope has many components, request to have it packed in a wooden crate.
- Confirm that there is no physical damage or any misaligned internal components.
- Ask what accessories are included.
- Ask how long the warranty is and what it covers.
Here is what our technical team tests so you can request something similar and ensure your microscope will be fully functional.
- We confirm the microscope's physical condition.
- We meticulously inspect and clean the optical path within the microscope.
- We assess light quality using various fluorescence and non-fluorescence samples.
- We ensure the stage moves smoothly in both fine and coarse adjustments.
- We ensure the smooth operation of all mechanical components.
- We confirm that all electronic/motorized components are working well.
- We set up communication between the microscope, installed components, and the software.
- We test the camera by acquiring sample images.
- We confirm the responsiveness of any included touchscreens and buttons.
- We ensure necessary accessories and cables are included.
We recommend inspecting the microscope in person with your sample or requesting a virtual demo; this will allow you to evaluate the condition and performance of the microscope you are considering purchasing.
Do you have a Leica DMi8 Inverted Microscope on hand?
- Yes, this is a common microscope model we carry, and we stock multiple accessories and many replacement parts to back up our warranty.
I found it elsewhere for less. What goes into your price?
We acknowledge that sometimes you can purchase this microscope model elsewhere, possibly for less.
Here are some of the reasons for our price.
- Our microscope will be fully serviced.
- It will be customized and configured to your requirements.
- We may offer longer standard warranty terms.
- We cover shipping costs during the warranty period. (Customer is required to save packing materials for the duration).
- We have to employ technical staff that can do the testing/repairs and after-sales support if there are any issues.
- We invest considerable time into the testing and service of each microscope we sell.
- We have to purchase any missing required accessories to make the microscopes complete.
- We have to procure and stock service parts to fulfill our warranty.
- We have extensive experience packing sensitive instruments. See the shipping section in the website menu for info on how not to pack.
- We guarantee that the microscope will be functional.
This procurement is for a University or College. Are purchase orders with NET terms accepted?
- If you are a US or Canadian customer, we are likely already a registered vendor in your University's vendor system. This would greatly expedite the process of PO approvals and get this instrument into your lab faster.
- POs are accepted from US and Canadian universities.
How fast will you ship?
- We can ship within a few days to 2 weeks, depending on your required microscope customization.
Will my microscope be insured during shipping?
- All microscopes shipped within the USA and internationally are fully insured. This applies as long as we are the shipper and handle shipping arrangements.
- If the buyer handles shipping, then shipping insurance responsibility falls to the buyer; we highly advise that the buyer obtain shipping insurance from their carrier.
How do you pack? Have you previously packed and shipped a Leica DMi8 Inverted Microscope? Do you ship Internationally?
Packing
- Smaller microscopes ship via UPS Parcel Delivery with adequate packing material and a strong box. Or, when combined with other orders, it may be packed in a crate.
- Most larger microscopes ship in fully enclosed ISPM15-certified wooden crates with proper padding underneath, and the sides have moving components braced.
- Accessories are packed safely in boxes with padding and then safely packed inside the crate.
- We may not use a crate for local deliveries to save you money *if delivered by us.
- We often use “tilt’ & “shock” indicators on the crates to ensure the crate has not been excessively tilted and dropped where equipment may suffer damage.
- Photos are taken during the packing process to make sure nothing is missed.
USA/Canada Shipping
- Within the US and Canada, we will ship via selected freight carriers. We do not use low-price/high-damage carriers as we want the equipment to get safely to you.
International Shipping
- Internationally, we will only ship via Air Freight or Air Parcel (such as UPS or DHL), which provides reliability, no exposure to Ocean weather, and timely delivery.
We have extensive experience packing and shipping fragile microscopes globally.
Our experience and process
- We have safely packed and shipped thousands of sensitive analytical instruments.
How much will I save buying it pre-owned, and is it worth it?
A lot…and it is undoubtedly worth it, and here is why. Feel free to ask for feedback from hundreds of customers who bought from us.
- When compared to buying a new one, you will save up to 60% to 80% and have plenty of funds left over for an additional instrument or two.
- You will get our standard warranty, plus, when available, an option to obtain an extended warranty agreement.
- Know that your microscope was tested and working the day it left our facility and is covered if there are faults.
Sustainability
- Well, this one is easy: buying a pre-owned microscope is great for the planet; you are reducing unnecessary waste, CO2 output, and water use that would be used during the manufacturing process.
I have more questions; I want to receive a formal quote.
Absolutely! Please give us a call (1-617-397-3486) or complete this form to get your questions answered or receive a formal Quote.
Manual for Leica DMi8 Inverted LED Fluorescence Encoded Microscope (New Filters)